Rodent Research-2 Center for the Advancement of Science in Space (RR-2 CASIS): Kelly performed a fixative flush and swapped the samples collected yesterday which he inserted into MELFI. The primary objective of this research is to monitor the effects of the space environment on the musculoskeletal and neurological systems of mice as model organisms of human health and disease. Living in microgravity results in significant and rapid effects on the physiology of mice that mimic the process of aging and some diseases in humans on Earth, including muscle atrophy and the loss of bone mineral density. This project will help scientists to discover new molecular targets that can facilitate the development of novel therapeutics for the treatment of muscle and bone-related diseases. Long-duration exposure to microgravity will also induce changes in gene expression, protein synthesis, metabolism, and eye structure/morphology that will be identifiable as a series of assessable biomarkers for tracking the onset and progression of disease. 1-Year Mission (1YM) Human Research Program (HRP) Science Operations: Kelly performed the following suite of HRP activities today. The Sleep ISS-12 experiment monitors ambient light exposure and crew member activity and collects subjective evaluations of sleep and alertness to examine the effects of space flight and ambient light exposure on sleep during a year-long mission on the ISS. In the Fine Motor Skills experiment, crew members perform a series of interactive tasks on a touchscreen tablet. The investigation is the first fine motor skills study to measure long-term microgravity exposure, different phases of microgravity adaptation, and sensorimotor recovery after returning to Earth gravity. Individualized Real-Time Neurocognitive Assessment Toolkit for Space Flight Fatigue (Cognition) is a battery of tests that measure how spaceflight-related physical changes, such as microgravity and lack of sleep, can affect cognitive performance. Cognition includes ten brief computerized tests that cover a wide range of cognitive functions, and provides immediate feedback on current and past test results. The software allows for real-time measurement of cognitive performance while in space. Combustion Integration Rack (CIR) Hardware Gather: Virts gathered the equipment for the CIR reconfiguration from FLame Extinguishment Experiment (FLEX)-2 to the FLEX-2J scheduled for Wednesday. Node 1 (N1) and Node 2 (N2) Bacteria/Charcoal Filter Remove & Replace (R&R): Virts removed N1 bacteria filters and replaced them with charcoal filters. Using charcoal filters in Node 1 will reduce the ISS atmospheric Polydimethylsiloxane (PDMS) concentration. Reducing the PDMS atmospheric concentration will subsequently reduce the quantity of dimethylsilanediol (DMSD) produced in the Common Cabin Air Assembly (CCAA) Condensing Heat Exchangers, thereby extending the life of the Multifiltration (MF) Beds that are in a zero spare posture. The bacteria filters that were removed from the N1 will replace the N2 Bacteria filters that were scheduled to be replace per preventative maintenance schedule. Robotics Refueling Mission (RRM) Hardware Removal: Following the conclusion of last week’s RRM activities, Cristoferetti extended the JEMAL Slide Table (ST) into the Japanese Experiment Module Pressurized Module (JPM), brought the RRM Task Board-2 and Safety Cap Tool (SCT) into the ISS habitable volume and removed them from the JEMAL ST. The ST was then retracted from the JPM side and the inner hatch was closed. Node 1 (N1) Stowage/Relocation: Cristoferetti began this activity to move infrequently used hardware from N1 to Permanent Multipurpose Module (PMM)-1. This is to create space in the N1 for food stowage and the Galley Rack scheduled to arrive in August on H-II Transfer Vehicle (HTV)-5. Dragon Cargo Transfer Operations: As of today, the crew has approximately 11 hours of SpX-6 cargo operations remaining. Today’s Planned Activities All activities were completed unless otherwise noted. SLEEP – Questionnaire Regeneration of БМП Ф2 Micropurification Cartridge (start) Cleaning fan grilles on FGB interior 201, 301, 401 PROX Power Switch ON Life On The Station Photo and Video Node 1 Stowage – Part 3 CIR Hardware Gather FINEMOTR – Experiment Ops RRM. OBT, Procedure Overview Cleaning fan grilles on FGB interior panels 116, 316, 231, 431 Robotic Refueling Mission (RRM) Removal Procedure Review MRM1-FGB Screw Clamp Tightening JEM Airlock Slide Table (ST) Extension to JPM Side DRAGON. Transfers Ops Verification of ИП-1 Flow Sensor Position RRM. Hardware Assembly VIZIR. Experiment Ops Dust Filter Replacement and MRM1 Gas-Liquid Heat Exchanger Cleaning Activation of FS1 File Server. JEM Airlock – Slide Table Retraction СТТС Configuration for MRM2 Heart Rate Monitor (HRM) iPad Data Transfer to ISS Server WRS – Recycle Tank Fill from EDV Testing iPAD full network access capabilities on the RS. Replacing ИДЭ-3 Smoke Detectors in MRM2 PROX Switch OFF DRAGON. Transfers Ops Audit of ВП1 fuses in SM Rodent Research (RR) – Fixative Swap Node 1 Bacteria/Charcoal Filter Remove and Replace DRAGON. Transfers Ops ALGOMETRIA. Experiment Ops Test activation of Vozdukh Atmosphere Purification System Emergency Vacuum Valves ISS RS Plug-In Audit Changeout of Dust Filter Cartridges in SM Dragon -Transfers Tagup Node2 Bacteria/Charcoal Filter Remove and Replace Dragon Cargo Operations Conference СОЖ Maintenance Rodent Research (RR) – Sample MELFI Insertion MSG – Powerdown Rodent Research (RR) – Cleaning Animal Access Unit WRS – Recycle Tank Fill from EDV IMS Delta File Prep Historical Documentation. Photography of Synthetic Muscle Relocate Rodent Tissue Boxes returning on SpX-6 and stow ACE Heated sample which arrived on SpX-6 CIR – Post-Experiment Hardware Stowage MDCA – Multi-User Droplet Combustion Apparatus MWA Prep COGN – Experiment Ops and Questionnaire БМП Ф2 Absorption Cartridge Regeneration (end) Completed Task List Items None Ground Activities All activities were completed unless otherwise noted. N3 CDRA Bed Leak Check HTV5 Prox Ops Checkout Three-Day Look Ahead: Wednesday, 05/13: Twin Studies, RR habitat stow, MDCA h/w replace, SAM install, N3 Power reconfiguration, IMAK unpack Thursday, 05/14: N1 and N3 SDS Valve Install, HXP sampling Friday, 05/15: Restocking rodent habitat, Micro Observatory sampling, FPEF MD10 removal QUICK ISS Status – Environmental Control Group: Component Status Elektron On Vozdukh Manual [СКВ] 1 – SM Air Conditioner System (“SKV1”) On [СКВ] 2 – SM Air Conditioner System (“SKV2”) Off Carbon Dioxide Removal Assembly (CDRA) Lab Operate Carbon Dioxide Removal Assembly (CDRA) Node 3 Standby Major […]
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