ISS Daily Summary Report – 06/07/15

Rodent Research-2 Center for the Advancement of Science in Space (RR-2 CASIS): Kelly and Virts successfully completed the final of four sample collection sessions today.  Kelly was the primary operator while Virts assisted, placing samples in containment then in MELFI.  The primary objective of this research is to monitor the effects of the space environment on the musculoskeletal and neurological systems of mice as model organisms of human health and disease. Living in microgravity results in significant and rapid effects on the physiology of mice that mimic the process of aging and some diseases in humans on Earth, including muscle atrophy and the loss of bone mineral density. This project will help scientists to discover new molecular targets that can facilitate the development of novel therapeutics for the treatment of muscle and bone-related diseases. Long-duration exposure to microgravity will also induce changes in gene expression, protein synthesis, metabolism, and eye structure/morphology that will be identifiable as a series of assessable biomarkers for tracking the onset and progression of disease.  Today’s Planned Activities All activities were completed unless otherwise noted. SLEEP. Completing Questionnaire. TWIN. Sample Collection HRF – Sample Collection and Stow Prep Rodent Research (RR) – Experiment Ops, Part 1A RR – Experiment Ops, Part 1B RR- Installation of Refrigeration Centrifuge RR- The mice bone densitometer scan RR – Sample MELFI Insertion RR – Bone densitometer scan RR – Sample MELFI Insertion RR – Sample MELFI Insertion RR – Refrigeration Centrifuge Configuration RR – Experiment Ops, Part 1В RR- Closeout Ops RR – Sample MELFI Insertion SOZH Maintenance. RR- Experiment Ops, Part 2A RR- Experiment Ops, Part 2B RR- Bone densitometer scan RR – Sample MELFI Insertion RR – Sample MELFI Insertion RR- Bone densitometer scan RR – Sample MELFI Insertion RR – Sample MELFI Insertion RR- Refrigeration Centrifuge Configuration RR- Hardware Stowage RR- Experiment Ops, Part 2В RR- Closeout Ops RR – Sample MELFI Insertion Completed Task List Items  N/A  Ground Activities All activities were completed unless otherwise noted. Rodent Research Ops Three-Day Look Ahead: Monday, 06/08: Rodents Research fixative swap, OBT Soyuz drill, Emergency roles/responsibilities review Tuesday, 06/09: EMU 3010 Return To Service (part 1), EMU 3005 FPS pack for return, Crew Quarters deck cleaning, Fine Motor Skills, Cardio Ox Ultrasound Wednesday, 06/10: Crew Quarters starboard cleaning, Twin Studies, Change of Command ceremony, crew departure prep QUICK ISS Status – Environmental Control Group:                               Component Status Elektron Off Vozdukh Manual [СКВ] 1 – SM Air Conditioner System (“SKV1”) On [СКВ] 2 – SM Air Conditioner System (“SKV2”) Off Carbon Dioxide Removal Assembly (CDRA) Lab Standby Carbon Dioxide Removal Assembly (CDRA) Node 3 Operate Major Constituent Analyzer (MCA) Lab Shutdown Major Constituent Analyzer (MCA) Node 3 Operate Oxygen Generation Assembly (OGA) Process Urine Processing Assembly (UPA) Reprocess Trace Contaminant Control System (TCCS) Lab Off Trace Contaminant Control System (TCCS) Node 3 Full Up  

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