Cardio Ox: Kelly performed his Flight Day 300 (FD300) Cardio Ox ultrasound and blood pressure measurement session with Peake acting as operator. Throughout the day today, Kelly collected urine samples that will be used by the Cardio Ox and Twins Studies. Tomorrow, he will collect blood samples and store them in Minus Eighty Degree Celsius Laboratory Freezer for ISS (MELFI) until their return to ground for laboratory analysis. The goal of Cardio Ox is to determine whether biological markers of oxidative and inflammatory stress are elevated during and after space flight and whether this results in an increased, long-term risk of atherosclerosis risk in astronauts. Twelve crewmembers provide blood and urine samples to assess biomarkers before launch, 15, and 60 after launch, 15 days before returning to Earth, and within days after landing. Ultrasound scans of the carotid and brachial arteries are obtained at the same time points, as well as through 5 years after landing, as an indicator of cardiovascular health. Airway Monitoring: Peake configured equipment in the Lab for the Ambient Pressure monitoring session of the Airway Monitoring Experiment. Peake changed out the sensor for both the Low and High Nitric Oxide (NO) Analyzers. He then configured camera views and activated the Portable Pulmonary Function System (PPFS) prior to a software update performed by ground teams. The primary goals of the Airway Monitoring experiment is to determine how gravity and microgravity influence the turnover of NO in the lungs. During future manned missions to the Moon and to Mars, airway inflammation due to toxic dust inhalation is a risk factor. Since dust may cause airway inflammation and since such inflammation can be monitored by exhaled NO analysis the present study is highly relevant for astronaut health in future space programs. Ocular Health: This week Kopra and Peake are performing their FD30 Ocular Health activities. Today, the crew performed tonometry to measure intraocular pressure, blood pressure measurements, vision tests and a vision questionnaire. The Ocular Health protocol calls for a systematic gathering of physiological data to characterize the risk of microgravity-induced visual impairment/intracranial pressure in ISS crewmembers. Researchers believe that the measurement of visual, vascular and central nervous system changes over the course of this experiment and during the subsequent post-flight recovery will assist in the development of countermeasures, clinical monitoring strategies, and clinical practice guidelines. Extravehicular Mobility Unit (EMU) Loop Scrub: Kopra configured EMU suits 3008 and 3011 for loop scrubbing. During EMU 3011 loop scrub, a leak was observed at the Liquid Cooling and Ventilation Garment (LCVG) to water processing jumper connector. Photographs of the leak were taken and the area dried. An attempt to recreate the leak during iodination was unsuccessful. After the scrubbing activity was completed, he reconfigured hardware and performed Iodination of Ion Filters for both suits. Finally he performed a dryout of the EMU Fan Module and Vent Loop. Samples containing 250 mL of the water were obtained after the loop scrub activity to determine the effectiveness of the filtering. 10 mL of this water sample will be used for a conductivity test on Friday onboard ISS and the remaining water will be sent to the ground for chemical analysis. Nitrogen Oxygen Recharge System (NORS) Oxygen Transfer: The NORS Oxygen transfer to the high pressure O2 tanks was successfully completed yesterday. Early this morning, the ground teams commanded the NORS Oxygen transfer to the low pressure O2 tanks. Transfer to the low pressure tanks is complete and the crew has closed the transfer valve. Today’s Planned Activities All activities were completed unless otherwise noted. Laptop RS1(2) Reboot SLEEP – Questionnaire SM ПСС (Caution & Warning Panel) Test TWIN – Urine Sample Collection МО-8. Configuration Setup Body Mass Measurement HRF – Sample Insertion into MELFI Nitrogen Oxygen Recharge System (NORS) – Oxygen Transfer to Low Pressure O2 Tank Fine Motor Skills Soyuz 718 Samsung Tablet Recharge Eye Test (Ocular Health) – Blood Pressure Operations CRHYT – Hardware Removal HAM radio session from Columbus HMS Visual Testing Activity BIOCARD. Experiment Ops. Health Maintenance System (HMS) – Tonometry Test Configuration Eye Imaging (Ocular Health) Window Observational Research Facility (WORF) – Cable Installation Preparation of spacesuit replaceable elements, service and personal gear. USND2 CARDOX Airway Monitoring (AIRMON) EMU cooling loop scrub RADIN – Handover of Detectors to RS MATRYOSHKA-R. Handover of BUBBLE-dosimeters from USOS HRF Blood Collection RS ПН28-120Power Converter Checkout. ПхО and DC1 config for EVA 42 EMU Cooling Loop H2O Sample PAO Event with the 1 Year Mission crew Inspection and Cleaning of Laptops RS2, RS3 IPAD Configuration for Dose Tracker VEG-01 HABIT RS1 Laptop Inspection and Cleaning. JRNL – Journal Entry INTERACTION-2. Experiment Ops IPAD Configuration for Dose Tracker Health Maintenance System (HMS) – Nutritional Assessment (ESA) СОЖ Maintenance EMU – Long Dryout ISS Emergency OBT Review COGNITION Completed Task List Items WHC KTO Replace Ground Activities All activities were completed unless otherwise noted. TRRJ Survey, Nominal System Commanding Three-Day Look Ahead: Thursday, 01/21: ISS Emergency Training, Fundoscope, Airway Monitoring Friday, 01/22: RRM Taskboard 4 Removal from JEMAL, ELF, OcularHealth, HMS Ultrasounds, Airway Monitoring Stow Saturday, 01/23: Crew Off Duty, Weekly Housekeeping QUICK ISS Status – Environmental Control Group: Component Status Elektron On Vozdukh Manual [СКВ] 1 – SM Air Conditioner System (“SKV1”) On [СКВ] 2 – SM Air Conditioner System (“SKV2”) Off Carbon Dioxide Removal Assembly (CDRA) Lab Operate Carbon Dioxide Removal Assembly (CDRA) Node 3 Override Major Constituent Analyzer (MCA) Lab Idle Major Constituent Analyzer (MCA) Node 3 Operate Oxygen Generation Assembly (OGA) Process Urine Processing Assembly (UPA) Standby Trace Contaminant Control System (TCCS) Lab Full Up Trace Contaminant Control System (TCCS) Node 3 Off
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