Fluid Shifts Operations In the Service Module: With ground team assistance, crewmembers configured the Optical Coherence Tomography (OCT) hardware, the Cerebral and Cochlear Fluid Pressure (CCFP) analyzer, and the Distortion Product Otoacoustic Emission (DPOAE) hardware before conducting a DPOAE test, OCT exam, and the Tonometry exam. The scheduled CCFP test was not completed due to software issues that could not be resolved during the Chibis session. However ground teams confirmed that the OCT, Tonometry and DPOAE exams were successfully completed. The purpose of this investigation is to characterize the space flight-induced fluid shift, including intra- and extravascular shifts, intra- and extracellular shifts, changes in total body water and lower vs. upper body shifts. Noninvasive techniques are used to assess arterial and venous dimensions and flow parameters, ocular pressure and structure, and changes in intracranial pressure. Lower body negative pressure is being investigated for its ability to mitigate some of the effects of the space flight-induced fluid shift. Results from this investigation are expected to help define the causes of the ocular structure and vision changes associated with long duration space flight and assist in the development of countermeasures. Heart Cells Microscope Operations: The crew set up the Heart Cells microscope, removed the BioCell Habitat from the Space Automated Bioproduct Lab (SABL) and the Multiwell BioCell from the BioCell Habitat and inserted into the microscope before completing Heart Cells operations. The Heart Cells investigation studies the human heart, specifically how heart muscle tissue, contracts, grows and changes (gene expression) in microgravity and how those changes vary between subjects. Understanding how heart muscle cells, or cardiomyocytes, change in space improves efforts for studying disease, screening drugs and conducting cell replacement therapy for future space missions. Mouse Epigenetics Cage Unit Maintenance: The crew completed standard maintenance activities for the Mouse Epigenetics experiment by exchanging the food cartridge of the Mouse Habitat Cage Unit which is located in the Cell Biology Experiment Facility (CBEF). The Mouse Epigenetics investigation studies altered gene expression patterns in the organs of male mice that spend one month in space, and also examines changes in the deoxyribonucleic acid (DNA) of their offspring. Results from the investigation identify genetic alterations that happen after exposure to the microgravity environment of space. Dose Tracker: The crew completed entries for medication tracking today. This investigation documents the medication usage of crewmembers before and during their missions by capturing data regarding medication use during spaceflight, including side effect qualities, frequencies and severities. The data is expected to either support or counter anecdotal evidence of medication ineffectiveness during flight and unusual side effects experienced during flight. It is also expected that specific, near-real-time questioning about symptom relief and side effects will provide the data required to establish whether spaceflight-associated alterations in pharmacokinetics (PK) or pharmacodynamics (PD) is occurring during missions. NanoRacks External Platform (NREP) Preparation: In preparation for tomorrow’s NREP installation operations on the Japanese Experiment Module (JEM) Airlock (JEMAL) Slide Table, the crew reviewed operation information and gathered hardware to support NREP assembly activities. Extravehicular Activity Mobility Unit (EMU) checkout: The crew retrieved Extravehicular Activity Mobility Unit (EMU) 3006 which was delivered on SpX-9 and installed it on the Forward EMU Don/Doff Assembly (EDDA). The crew then performed an initial checkout of EMU systems to confirm suit 3006 as a viable spare prior to returning the previous spare (EMU 3005) on SpaceX-9. Patch Uplink for ETCS Loop Startup Freeze Protection: Ground teams uplinked a patch to the EXT and S0 MDMs. This patch provides a Fault Detection, Isolation, & Recovery (FDIR) to limit the amount of time that cold ammonia can flow through the External Thermal Control System (ETCS) during startup, to prevent the Interface Heat Exchanger (IFHX) from freezing if there is cold ammonia flowing through the ETCS with stagnant water present in the IFHX. The new FDIR will cut power to the pumps when this timer expires and stop the flow of ammonia. The new FDIR has been enabled. Wastewater Storage Tank Assembly (WSTA) Drain and Multifiltration (MF) Bed #2 Effluent Sample The Urine Processor Assembly (UPA) WSTA was drained into an EDV and subsequently refilled. A sample will be taken from this EDV later this week to address high conductivity seen in the UPA. The Water Processor Assembly (WPA) MF bed was also drained so that a sample could be taken to address high conductivity in the WPA. After the sample was collected, WPA was put back in standby. Both samples will be returned to ground on SpaceX-9. On Board Training (OBT) Medical Emergency: The 47S crew participated in this training which provides the opportunity to review procedures, hardware and communication methods necessary to manage a medical emergency. Specific topics covered included: Emergency medical hardware configuration and desired deployment locations. Individual preference for performing chest compressions in microgravity. Crew communication and coordination of care during an emergency medical event. Today’s Planned Activities All activities were completed unless otherwise noted. FLUID SHIFTS. OCT Setup in SM FLUID SHIFTS. Comm configuration for the experiment / r/g 9995 FLUID SHIFTS. Gathering and Connecting Equipment for TV coverage FLUID SHIFTS. Connecting OCT Laptop to RS BRI and HRF PC to ППС-26 (Instead of RSE-Med) r/g 2978 CASKAD. Manual Mixing in Bioreactor / r/g 2888 Acoustic Dosimeter Setup Day 2 FLUID SHIFTS. OCT Power up in SM Soyuz 731 Samsung Tablet Recharge, Initiate MOUSE Gather Hardware for the Experiment LDST. Drawer Installation FLUID SHIFTS. TONO Hardware setup in SM Dust Filter Replacement and MRM1 Gas-Liquid Heat Exchanger (ГЖТ) Cleaning On-orbit Hearing Assessment using EARQ FLUID SHIFTS. CCFP Activation and Settings Adjustments in RS [Aborted] Multi Omics. Item gathering MCRSCPE Hardware Setup FLUID SHIFTS. DPOAE Setup in SM DOSETRK iPad data entry FLUID SHIFTS. Chibis Setup / r/g 2979 FLUID SHIFTS. Operator Assistance with Chibis and Gamma-1 r/g 2979 XF305 Camcorder Settings Adjustment FLUID SHIFTS. Gathering Data in SM, Subject [CCFP activity aborted] FLUID SHIFTS. Gathering Data in SM, Operator [CCFP activity aborted] Mouse Habitat Cage Unit Maintenance, Refilling water and exchanging Food Cartridge [Water refill […]
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