Microbial Tracking-2 (MT-2): The crew collected saliva and body samples for the Microbial Tracking-2 investigation and placed them inside a Minus Eighty Degree Celsius Laboratory Freezer for ISS (MELFI). After the samples are returned to Earth, a molecular analysis of the RNA and DNA will be conducted to identify the specific microbes that are present on ISS. MT-2 monitors the different types of microbes that are present on ISS over a 1-year period and how they change over time. Efficacy and Metabolism of Azonafide Antibody-Drug Conjugates in Microgravity (ADCs in Microgravity): The crew viewed ADC cells with a microscope and fixated the BioCells. The ADCs in Microgravity investigation evaluates new antibody-drug conjugates that combine an immune-activating drug with antibodies in order to target only cancer cells, increasing the effectiveness of chemotherapy and reducing its side effects. In microgravity, cancer cells grow in three-dimensional, spheroid structures that closely resemble their form in the human body, allowing for better drug testing. This investigation may accelerate development of targeted therapies for cancer patients. Sprint Volume of Oxygen Utilized (VO2) Maximum: The crew set up and performed a Sprint VO2 Max exercise protocol today. The subject completed their Flight Day 105 session with assistance from the other USOS crewmember. The Sprint investigation evaluates the use of high intensity, low volume exercise training to minimize loss of muscle, bone, and cardiovascular function in ISS crewmembers during long-duration missions. Habitability: The crew narrated a task video while they tore down the microscope hardware used for the ADCs in Microgravity investigation. The Habitability investigation collects observations about the relationship between crewmembers and their environment on the ISS. Observations can help spacecraft designers understand how much habitable volume is required, and whether a mission’s duration impacts how much space crew members need. Node 3 to Node 1 Sample Delivery Systems (SDS) Power Jumper Installation: The crew installed the SDS Power Jumper in the Node 1 to Node 3 Vestibule and mated the SDS Power Cable to the Node 3 bulkhead. This activity is part of the ISS Reconfiguration plan and is required to provide samples for the Major Constituent Analyzer (MCA) in support of visiting vehicles berthed to Node 1. Today’s Planned Activities All activities were completed unless otherwise noted. Microbial Tracking-2 Sample MELFI Insert Combustion Integrated Rack Alignment Guide Removal Antibody Conjugates Microscope Operations Voice check in S/G1 from Baikonur JEM System Laptop Terminal (SLT) swapping from SLT 4 to SLT 6 Part 1. Collect SM and FGB Air Samples Using АК-1М Sampler Antibody Conjugates Biocells Fixation JEM System Laptop Terminal (SLT) swapping from SLT 4 to SLT 6 Part 2. SM Air Sampling for FREON Using АК-1М Sampler ИПД Air Sample Collection for Ammonia in SM В3 Fan Screen Cleaning in DC1 JEM System Laptop Terminal (SLT) swapping from SLT 4 to SLT 6 Part 3. JEM System Laptop Terminal (SLT) Activation Antibody Conjugates MELFI Sample Insertion Habitability Narrated Task Video Setup – Subject Plant Exp Unit Checkout Item Gather Microscope Hardware Teardown SPLANKH. Termination EGEG Recording and Closeout Ops Galley Rack Configure Habitability Narrated Task Video End – Subject HRF2 PC 2 USB Load Installation Preparation Food Acceptability Questionnaire – Subject Sprint Portable Pulmonary Function System Setup Partial Sprint Portable Pulmonary Function System Power Up RS2, RS3 Laptops Inspection And Cleaning Crew Medical Officer (CMO) Proficiency Training Sprint VO2 Operations – Subject On MCC Go RS1 Laptop Inspection and Cleaning MARES Ultrabay Hard Disk installation Crew Support LAN (CSL) 3 hard drive swap & Reload Sprint Portable Pulmonary Function System Stow Partial Measuring CO partial pressure at Central Post using CSA-CP analyzer Replacement of CO2 Filter Unit ИК0501. Antibody Conjugates MSG Hardware Teardown ADC Thaw System Trash Emergency OBT iPad Network Connectivity Test HRF2 PC 2 USB Load Installation Conclude Tropical Cyclone Untended Operations RADIOSKAF. Closeout Ops RADIOSKAF. Nanosatellite Prep Ops prior to EVA Completed Task List Items Node 3 Sample Delivery System Power Jumper Installation [In Work] Ground Activities All activities were completed unless otherwise noted. ADC B Cell fixation support Rodent Research habitat video Three-Day Look Ahead: Thursday, 07/27: Capillary Structures, CBEF ops Friday, 07/28: 51S Launch, RR gather/procedure review Saturday, 07/29: Crew off duty QUICK ISS Status – Environmental Control Group: Component Status Elektron Off Vozdukh Manual [СКВ] 1 – SM Air Conditioner System (“SKV1”) Off [СКВ] 2 – SM Air Conditioner System (“SKV2”) On Carbon Dioxide Removal Assembly (CDRA) Lab Operate Carbon Dioxide Removal Assembly (CDRA) Node 3 Standby Major Constituent Analyzer (MCA) Lab Idle Major Constituent Analyzer (MCA) Node 3 Operate Oxygen Generation Assembly (OGA) Standby Urine Processing Assembly (UPA) Standby Trace Contaminant Control System (TCCS) Lab Full up Trace Contaminant Control System (TCCS) Node 3 Off
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